Showing posts with label chronic pain. Show all posts
Showing posts with label chronic pain. Show all posts

Friday, May 29, 2009

Treatment History of Cannabis References Shaking Palsy

A brief the summary of Cannabis as medicine before moving on to PD
While smoking may seem to be a modern form of usage, marijuana has long been used as a tea, an edible extract, as a paste or powdered. That history goes back almost 5,000 years in China and India where it was used as a painkiller to treat chronic pain. The Greeks and Romans did use cannabis for treatment of pain, rheumatism and gout although the Romans who certainly knew about excess were concerned about its effect on sexual performance if used too much or too often. In Egypt there is evidence that it was used to treat glaucoma as well as pain. Tomb evidence points to applications orally, rectally, vaginally for labor pain; dermally, apparently inserted in the eye area and also smoked.

The reintroduction of marijuana to the western world occurred in the mid 1600s when it was made into a paste or plaster for for rheumatism, gout, burns and tumors. Two hundred years later Dr William Brooke O'Shaughnessy, an Assistant-Surgeon and Professor of Chemistry in the Medical College of Calcutta learned about cannabis when practicing in India. Although the areas he explored did not involve Parkinson's, he did report some success with acute Rheumatism in a paper he presented in 1839 on On The Preparations of the Indian Hemp, or Gunjah

In 1860 the Ohio State Medical Society issued a report on Cannabis Indicia by the Chairman on Cannabis Indicia, Dr R R McMeens, with contributions of several doctors and referencing Dr O'Shaughnessy as well. In it are descriptions of using cannabis to treat epilepsy with some success, glottal spasms and spasming of fingers and toes as well as asthma. On page 8 there is a reference to using it to treat "shaking palsy."

The Indian Hemp Drugs Commission (1893-94) may have been established more as an effort to find ways levy taxes, but it was extensive, listened to an enormous amount of testimony from a broad spectrum of society and ultimately did indicate that it found no evil in moderation and indeed that hemp-cannabis was an effective treatment for many conditions.

To some extent the history of marijuana in the 20th century became a follow the money situation. Until 1937 there were more than 25 medicines on the US market which utilized marijuana. It was not until the Marijuana Tax Act of 1937 prohibited marijuana that these were no longer available. While other pharmacopoeia were already replacing these medications, there was still a significant market and one which might have continued to develop. At the same time the use of hemp oil for paint and varnishes was usurped by DuPont petrochemicals.

Since the controlled Substances Act of 1970 successfully made its dishonest claims law, marijuana was quietly ignored as having medical value and development potential. What does this say about our national ethos that we could accept the mistruths, the lies? the sellouts? Is it also a commentary about our fear level? Not just the fear of our own diseases or physical conditions but rather the fear of people with diseases and conditions? Our fear of ourselves and our government? The fear that we will lose everything?

While people are going to hold their residual prejudices and studies will be limited, that should not exclude serious research. It should be noted that people are not looking for a cure but for symptomatic relief from conditions which affect not only the patient but also the caregiver and the families. Something to restore-improve quality of life.

A Most Interesting Book

September 2011 update
A list of States where the courage and compassion has been found to decriminalize Medical Marijuana possession and/or cultivation.

Wednesday, May 27, 2009

Medical Marijuana for Parkinson's Disease

Maybe the Grass Is Greener...

Everyone who has read Parkinson's Focus Today knows that Steve has arthritis in his knees. It is very unpleasant in his left knee - his PD side. He has trouble walking, hates to kneel because of the constant pain and has a real problem rising from a kneeling position. Which means, no more plumbing repairs around the house; no display of that plumbers' butt crack. Because he needs a cane to walk, that means no more toting things that need to be moved around. That's kind of inconvenient for me because it means there's just one of us to do the lifting. He is the consultant now.

So a few weeks ago we were trying to snake a graywater drain and I managed to cut up my arms and hurt my thumbs repeatedly and badly. Long boring story but suffice it to say, I had blood dripping, deep abrasions on my thumbs - the wound on one thumb just stopped hurting this morning. (Note: vitamin A & D works better than vitamin E when applied directly to the scabbed area.) The snaking process took place over two weekends during which I managed to reopen the abrasions on both thumbs. I sprayed painkiller every hour to thumbs and arms for several days before easing off to a couple of times a day. And I have a high pain tolerance.

At some point I dug my nails into my palms to try to determine my pain level...or something. That gave me an idea. I wanted to find out how much that knee hurt him. So I took out my trusty hand, pushed those nails into his arm and asked him to tell me when the nails hurt more than the knee. I'm still strong but it took a lot of pressure - far more than the thumb test. So I would say that his pain level is moderately high. Not as high nor as consistent as pains from other conditions but far more painful than my raw burn-like skin which healing and would end.

Which brings me to the point...at last...I'm not one of those old hippy-dippys - I was a Girl Scout leader before I had children...so I didn't do drugs (unlike a former President)...but I am a believer in the use of Medical Marijuana to deal with a variety of conditions, diseases and pain. I know that mj relieves some asthma symptoms quite effectively. I know that it is effective in dealing with glaucoma, cancer agonies. It is effective in nausea and vomiting, in wasting syndrome and appetite stimulation as well as neurological symptoms and muscle spasticity.

10/26/09 Correction:
Just last week after recommendation by a Medical Advisory Board, New Mexico added the following conditions to the list of those who can apply for the Medical Marijuana Program run by the New Mexico Department of Health: 
Severe chronic pain
They did not add the following inflammatory and/or neurodegenerative conditions:
Severe osteoarthritis, Rheumatoid arthritis, Reactive arthritis
Post-polio syndrome
Parkinson's disease
Alzheimer's disease
Inclusion Body Myositis - chronic muscle inflammation and weakness as well as severe chronic pain
The Board under Secretary Alfredo Vigil, MD did not feel there was enough clinical evidence to substantiate the inclusion of the above conditions.

The above conditions would have been added to the list which included:
Painful peripheral neuropathy
Damage to the nervous tissue of the spinal cord with intractable spasticity
Intractable nausea/vomiting
Severe anorexia/cachexia
Hepatitis C infection currently receiving antiviral treatment
Crohn's disease
Post-traumatic Stress Disorder
Amyotropic Lateral Sclerosis (ALS-Lou Gehrig's disease)
Cancer
Glaucoma
Multiple Sclerosis (MS)
Epilepsy
HIV/AIDs
Hospice patients

The application for the New Mexico program can be found at http://www.nmhealth.org/marijuana.html You must have a debilitating condition and one which is not helped by standard treatment. Your physician must have informed you of the associated potential risks and benefits. While I know that my husband wouldn't qualify by any current standards as the hinged knee brace offers some assistance for support which relieves some pain; I also know that there are hundreds of thousands of people who are in much worse condition and should qualify.

Only 47 of the 295 applicants have been approved since the New Mexico program inception in July 2007. By contrast in Colorado there are 5,920 patients with registration cards. California, New Mexico and Rhode Island will be the only states which actually allow medical marijuana dispensaries. States with pending legislation, however limited include: Alabama, Connecticut, Illinois, Iowa, Minnesota, Missouri, New Hampshire, New Jersey, New York, North Carolina, Pennsylvania, Tennessee

The Supreme Court declined to hear the challenge the validity of the California law.

One last observation. Forget that old "if they try it they'll move on to..." the above symptoms are horrendous and some patients are hoping that they can reduce their morphine and other very strong stuff with some unpleasant side effects and to improve their quality of life. We'll be revisiting this topic.

Sources and resources I'll bet you never thought you'd see here:
http://www.nationalpainfoundation.org/articles/112/marijuana-and-pain-management
http://www.torontohemp.com/phpBB2/viewtopic.php?t=2412&sid=a43e9830121eb0ed1f8ed80439dbd529
http://www.nap.edu/catalog.php?record_id=6376
http://www.gazette.com/articles/marijuana-52851-research-patients.html
http://www.artesianews.com/new-health-condition-added-to-medical-cannabis-program/
http://www.mpp.org/
http://cannabisnews.com/news/24/thread24782.shtml
http://www.marijuana.com/drug-war-headline-news/121597-ny-should-marijuana-legally-prescribed-pain-reliever-new-york.html
http://www.vaughns-1-pagers.com/medicine/painkiller-comparison.htm
http://www.cannabismd.net/endocannabinoids/
http://en.wikipedia.org/wiki/Nabilone
http://www.ncbi.nlm.nih.gov/pubmed/17336288

2011 Addendum: